normal urine osmolality

Urine osmolality ranges from 50-1200 mOsmolkg. An increase in osmolality causes the gland to secrete antidiuretic hormone ADH resulting in water reabsorption by the kidney and an increase in urine concentration.

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The key is to always compare to serum osmolality to establish a pathological condition.

. Both parameters directly correlate. The two factors work together to return the plasma osmolality to its normal levels. For example a USG of 1010 approximates to a urine osmolality of 300 mOsmkg. Paired serum and urine osmolality are measured in patients with abnormal sodium or water balance as the relative values can help identify the likely cause of low blood sodium high blood sodium high.

Under normal conditions blood and urine osmolality are dependant on each other as urine osmolality changes to maintain a normal blood osmolality. It is more reliable and accurate than USG for evaluating kidney function.

Urine Osmolarity Pharmacology Nurse Facts